1stly welcome to DD
is it possible very much so, did you give us enough info , unfortunately not
1- are you planning to use miles or pay for the tkt
2- will you be spending Shabbos in europe and if yes do you want a city that has either a restaurant thats opened or a Chabad house that has meals
3- when in Europe what are you looking to do? does the weather matter? are you looking to stay in 1 place the whole week? do you want a daily minyon? etc etc
your post is way too General for an answer as it stands