You will be with 20 different yidden in a hotel, and everyone will tell you something else.
I ask for starters for a room that is on a lower floor.
The I use the tag of the check-in, which is mighty strong (see pic below), to cover the holes on the doorpost so that it doesnt lock when closing the door.
You might want to push some tissues in the holes before sticking it on.
I hang the Don't Disturb sign, but I'd put all valuables in a safe.