Author Topic: COVID-19 Reinfection  (Read 18269 times)

Offline AsherO

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Re: COVID-19 Reinfection
« Reply #360 on: May 26, 2021, 07:16:23 PM »
Great news!

https://medicine.wustl.edu/news/good-news-mild-covid-19-induces-lasting-antibody-protection/

How could they claim a lifetime of protection if COVIDís only been around for <1.5 years?

Iím not saying theyíre wrong, just trying to understand.

Offline gozalim

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Re: COVID-19 Reinfection
« Reply #361 on: May 26, 2021, 07:53:54 PM »
How could they claim a lifetime of protection if COVIDís only been around for <1.5 years?

Iím not saying theyíre wrong, just trying to understand.
read the article. something to do with bone marrow

Offline ae123

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Re: COVID-19 Reinfection
« Reply #362 on: May 26, 2021, 08:30:02 PM »
Breaking news. The science is slowly catching up to common sense.
Not really.
This was a relatively small study & they seem to be moving on to monitor immunity in vaccinated people.
I've actually been trying for some time through medical contacts to get studies done on natural immunity and oddly there doesn't seem to much interest. It's all "just take the vaccine".

Offline biobook

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Re: COVID-19 Reinfection
« Reply #363 on: May 26, 2021, 10:45:03 PM »
How could they claim a lifetime of protection if COVIDís only been around for <1.5 years?

Iím not saying theyíre wrong, just trying to understand.

After infection, B cells produce antibodies, but these cells have a short lifespan.  Some B cells become memory B cells, and have a longer lifespan.  Upon reinfection, they can quickly multiply and produce a large number of B cells that churn out antibodies.  So long-term immunity depends on these memory B cells. 

Based on general principles of immunity, it was assumed that memory B cells would be produced, though how long they last was uncertain.  Most of these memory B cells are sequestered in the bone marrow, so not exactly easy to study.  Here they found these memory B cells were still around 11 months after infection, so they're the kind of cells that are found in lifelong immunity, but I agree with you that they can't be certain that they'll last that long.  Some long-term immunity is on the order of a few years.