Poll

1 Or 2 Vaccine Doses For People Who Had COVID?

Get 1 dose and wait and see what updated guidance says
11 (50%)
Get 2 doses and be done with it
11 (50%)

Total Members Voted: 22

Author Topic: 1 Or 2 Vaccine Doses For People Who Had COVID?  (Read 13854 times)

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #160 on: August 23, 2021, 11:00:33 PM »
And until that science comes out, you think we should force them to vaccinate in the meantime?
We could wait on that group but I look at it as risk vs reward.
You're so far up Trump's a** you can see Giuliani's feet.  HT Baruch

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #161 on: August 23, 2021, 11:06:07 PM »
We could wait on that group but I look at it as risk vs reward.

"That group" is 36 million documented cases, and who knows how many undocumented ones. Not quite 1%....
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #162 on: August 23, 2021, 11:57:59 PM »
We could wait on that group but I look at it as risk vs reward.

You realize that the NY mandate which you suggested be copied by other states includes this group? People who were advised by their doctors to wait on the vaccine (every NY vaccination ad says "speak to your doctor") are not allowed to eat in restaurants and go to indoor events.
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #163 on: August 25, 2021, 02:44:12 PM »
BREAKING:

Israeli study finds that vaccination for previously infected people doesn't make a big difference.

https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1.full.pdf+html

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #164 on: August 25, 2021, 02:59:56 PM »
BREAKING:

Israeli study finds that vaccination for previously infected people doesn't make a big difference.

https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1.full.pdf+html
"big difference" is pretty broad. Do they state how much difference it does make?
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #165 on: August 25, 2021, 03:06:20 PM »
"big difference" is pretty broad. Do they state how much difference it does make?

Very little difference.

Model  3  - previously  infected  vs.  vaccinated  and  previously  infected  individuals In  model 3,  we  matched  14,029  persons.  Baseline  characteristics  of  the  groups are presented  in  Table  1b.  Examining  previously  infected  individuals to  those  who were both  previously  infected  and  received  a  single  dose  of  the vaccine,  we  found  that  the latter  group  had a  significant 0.53-fold  (95%  CI,  0.3  to  0.92)  (Table  4a)  decreased  risk for  reinfection,  as  20  had a  positive  RT-PCR  test,  compared  to  37  in  the  previously infected  and  unvaccinated  group.  Symptomatic  disease was  present  in  16  single  dose vaccinees  and  in  23  of  their  unvaccinated  counterparts. One  COVID-19-related hospitalization  occurred  in  the  unvaccinated  previously  infected  group.  No  COVID19-related  mortality  was  recorded. We conducted  a  further  sub-analysis, compelling  the  single-dose  vaccine  to  be administered  after  the  positive  RT-PCR  test.  This  subset  represented 81% of  the previously-infected-and-vaccinated  study  group.  When  performing  this  analysis, we found  a  similar,  though  not  significant,  trend  of  decreased  risk  of  reinfection,  with an OR of  0.68  (95%  CI,  0.38  to  1.21,  P-value=0.188).

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #166 on: August 25, 2021, 03:09:20 PM »
Very little difference.

Model  3  - previously  infected  vs.  vaccinated  and  previously  infected  individuals In  model 3,  we  matched  14,029  persons.  Baseline  characteristics  of  the  groups are presented  in  Table  1b.  Examining  previously  infected  individuals to  those  who were both  previously  infected  and  received  a  single  dose  of  the vaccine,  we  found  that  the latter  group  had a  significant 0.53-fold  (95%  CI,  0.3  to  0.92)  (Table  4a)  decreased  risk for  reinfection,  as  20  had a  positive  RT-PCR  test,  compared  to  37  in  the  previously infected  and  unvaccinated  group.  Symptomatic  disease was  present  in  16  single  dose vaccinees  and  in  23  of  their  unvaccinated  counterparts. One  COVID-19-related hospitalization  occurred  in  the  unvaccinated  previously  infected  group.  No  COVID19-related  mortality  was  recorded. We conducted  a  further  sub-analysis, compelling  the  single-dose  vaccine  to  be administered  after  the  positive  RT-PCR  test.  This  subset  represented 81% of  the previously-infected-and-vaccinated  study  group.  When  performing  this  analysis, we found  a  similar,  though  not  significant,  trend  of  decreased  risk  of  reinfection,  with an OR of  0.68  (95%  CI,  0.38  to  1.21,  P-value=0.188).

CMIIW, but doesn't this translate to cutting risk of infection by over 30%?
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #167 on: August 25, 2021, 03:12:21 PM »
Very little difference.
Am I reading this wrong (I am lost)?

Examining  previously  infected  individuals to  those  who were both  previously  infected  and  received  a  single  dose  of  the vaccine,  we  found  that  the latter  group  had a  significant 0.53-fold  (95%  CI,  0.3  to  0.92)  (Table  4a)  decreased  risk for  reinfection,

Weren't they less prone to get re-infected (infected + shot)?
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #168 on: August 25, 2021, 03:13:18 PM »
CMIIW, but doesn't this translate to cutting risk of infection by over 30%?
That would be a BIG difference.
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #169 on: August 25, 2021, 03:16:18 PM »
From a first glance at the abstract:

Compared:
people who got covid in Jan-Feb 2021
people who got vaccine in Jan-Feb 2021

Looked at how many got covid in June 1-Aug 14, when Delta predominant
Result:
Those who got the vaccine were 13 times as likely to get covid
Conclude:
Those with natural infection are better protected, (but this is looking at just 3-7 months after infection).

Compare:
people who got covid in March 2020-Feb 2021
people who got vaccine in Jan-Feb 2021
Result:
Those who got the vaccine were 6 times as likely to get covid
Conclude:
Immunity is waning after the natural infection, but not as quickly as it wanes after the vaccine.

Overall conclusion:
Natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.
« Last Edit: August 25, 2021, 04:28:28 PM by biobook »

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #170 on: August 25, 2021, 03:34:18 PM »
From a first glance at the abstract:

Compared:
people who got covid in Jan-Feb 2021
people who got vaccine in Jan-Feb 2021

Looked at how many got covid in June 1-Aug 14, when Delta predominant
Result:
Those who got the vaccine were 13 times as likely to get covid
Conclude:
Those with natural infection are better protected, (but this is looking at just 3-7 months after infection).

Compare:
people who got covid in Feb 2020-Feb 2021
people who got vaccine in Jan-Feb 2021
Result:
Those who got the vaccine were 6 times as likely to get covid
Conclude:
Immunity is waning after the natural infection, but not as quickly as it wanes after the vaccine.

Overall conclusion:
Natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.

Yup. The part I quoted above isn't in the abstract.

Compared to these numbers, it's not such a big deal at all.
A 30% benefit on something that is already extremely unlikely, isn't something very significant. 1% of new Israeli cases are reinfections. 104/10k yesterday for instance.

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #171 on: August 25, 2021, 03:35:17 PM »
CMIIW, but doesn't this translate to cutting risk of infection by over 30%?

30% for something already very unlikely is not a lot.

Full disclosure: I had covid and I'm fully vaxxed.

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #172 on: August 25, 2021, 03:37:10 PM »
30% for something already very unlikely is not a lot.

Full disclosure: I had covid and I'm fully vaxxed.
You're saying"very little difference" while quoting text that literally says "significant decreased risk".

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #173 on: August 25, 2021, 03:46:46 PM »
Why are they comparing infected + one shot? Shouldn't they have two shots?
You're so far up Trump's a** you can see Giuliani's feet.  HT Baruch

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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #174 on: August 25, 2021, 03:50:10 PM »
Why are they comparing infected + one shot? Shouldn't they have two shots?

I believe common practice was (is?) to treat the initial infection as the first 2 shots, and to give an additional shot as a booster.
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #175 on: August 25, 2021, 03:51:36 PM »
Why are they comparing infected + one shot? Shouldn't they have two shots?
How do we know that someone already infected still needs 2 shots? Maybe they only need one and the infections counts as the first? @ExGingi
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #176 on: August 25, 2021, 03:53:59 PM »
I believe common practice was (is?) to treat the initial infection as the first 2 shots, and to give an additional shot as a booster.

In the US prior infections are ignored.

In Israel, it was recommended that previously infected get one dose. IDK what the official recommendation is now that they are recommending a booster shot.

They seem to be making stuff up as they go along.
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #177 on: August 25, 2021, 03:55:44 PM »
They seem to be making stuff up as they go along.

That's kinda how this all works... Some people would even call it science.
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #178 on: August 25, 2021, 03:57:02 PM »
I believe common practice was (is?) to treat the initial infection as the first 2 shots, and to give an additional shot as a booster.
How do we know that someone already infected still needs 2 shots? Maybe they only need one and the infections counts as the first? @ExGingi
In the US prior infections are ignored.

In Israel, it was recommended that previously infected get one dose. IDK what the official recommendation is now that they are recommending a booster shot.

They seem to be making stuff up as they go along.
CDC (don't shoot me) says you should be fully vaccinated. I thought that meant 2 shots unless J&J would be 1.
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Re: 1 Or 2 Vaccine Doses For People Who Had COVID?
« Reply #179 on: August 25, 2021, 03:57:41 PM »
You're saying"very little difference" while quoting text that literally says "significant decreased risk".


You know the FDA wouldn't approve a vaccine with 30% efficacy. Right?