It makes sense to land in Ramon, since planes heading to Ben Gurion end up diverting out of the country (Ramon can't accommodate on short notice and foreign carriers likely knee-jerk response to escape entirely), and that disrupts passengers movements.
For take-offs, once the plane is in the air, there is no turning around. Domestic flights can be relatively confident of a safe landing before take-off, can always return to base, and have a strong political lobby.
Landings also take much longer than take-offs.
Fuel can be easily trucked to Ramon, it's the staff and security infrastructure that is much more difficult.