Cigarette smoke is hard to get rid of. It gets into fabrics and books. But it dissipates over time. An ozonator can help get rid of the smell. But slowly. And you will need to air out the ozone, but that's really quick.
My recommendation is to use the machine for a few days. Use the car for a few days and use the machine again. I don't know why, but I feel like you need to air things out in between. No scientific evidence.
Smoke from a fire is easier to remove. Maybe because it hasn't been absorbed into everything slowly over years' time.
Good luck.