And I'll come out and say it. I have a brother who is alive today only because of advice in Igros and I find my shidduch (albeit through a long chain reaction of events) from advice in Igros.
I've opened the Igros many times and not seen a relevant response (not saying it wasn't there).
There was one chapter in my life where I opened Igros three times and found a
very specific response (it's personal, so I can't share specifics, sorry), when checking the indexes/searching, it's a topic with low occurrence in Igros.