With the exception of Southern South America (Argentina, Bolivia, Brazil, Chile, Paraguay, and Uruguay) you have enough miles for both of you to fly round-trip anywhere in the world (including The US, Asia, Hawaii, Australia etc.) With creative routing, you can get in numerous free lay-overs less than 24 hours and at least 1 free stop-over.
In Business Class, you have enough miles to take you both numerous places, but the options are more limited.
Where are you interested in going....What do you want to do, Do you want to visit family, hotels, beaches, cities etc?