i personally would not use points for economy clas tickets as you can usually get them for a good price without getting ripped off.
aswell domestic flights are not worth using points as if you book well enough in advance you can get excellent prices.
their are exceptions of course , when domestic is expensive peak season etc, where i would use points.
but ive always used my points for international flight going business, i used to always get yyz-tlv business class on aircanada for 120,000 aeroplan points , but recently that has been impossible to get a business class ticket on air canada to tlv from toronto will cost 250 k points. so someone told me to book on star alliance with aeroplan points, they give me business class for 120k using lot,swiss,lufthansa, makeing a stop over which i totally dont mind as i always travel alone and never with the wife and kids.
so my opinion is points for business class only ! and only international