There are many potential issues.
- For starters you'll have to be hooked up to power - the batteries won't last all Shabbos and you can't/wouldn't want to run the generator instead. You'll probably also need 220v for the AC, so make sure the campground could supply that (many do).
- The water hookup may leak, which could be an issue of watering on shabbos; AYLOR.
- You can't put the cabin lights on a timer, so that may be an issue since some beds are in the main living area.
- Going in and out of the RV could be an issue of maaras ayin (even if no Jews are around), so you may have to cover up your wheels to indicate that you're staying put (obviously AYLOR).
-Make sure to empty the black water tank and treat the toilet before Shabbos; that's not something you want to get stuck with.
- Carrying anything outside is obviously an issue to discuss.
That'll all I could think of for now; I'm sure there are more