I'm not a stay at home dad, but for two years I watched my kids every Sunday while my wife went to college. (Sunday college).
Was not easy, but somehow once you know they are your responsibility for the whole day, you become a lot more patient and less anxious about when your wife is going to come home to "relieve" you.
I kind of agree with the "מלאכת נשים" comment, but it seems like in today's day and age, many נשים are not either cut out for it.