IIRC in his tshuva regarding the eruv in Brooklyn R Moshe himself writes that someone who understands the sugya differently is OBLIGATED to pasken based on the way he understands. Either, to take this further off topic, R Moshe's understanding of how to calculate 600,000 is definitely not the way it was understood by the Bais Efraim, Mishkenos Yaakov, R Aharon Kotler and many more. Someone who argues definitely has backers.