The natural right to self defense allows you to defend yourself in any way shape or form. The right protected by the constitution is up to the court to decide what is or is not included.
And if I wanted to defend myself with a nuke or explosives (perhaps plant them around my property to defend it), is that within my natural rights?
I don't think many people agree that you can defend yourself "in any way shape or form." Most historical and current laws I have seen limit the amount of force to that which is "reasonable," which is not defined by the defender, but by a judge or jury. On what basis do you believe that you can defend yourself in any way shape or form?